Copyright 2009 Advisory Panel Kaiser and Company Family Foundation. All rights reserved.. Acetaminophen over-use can result in serious liver damage By Dr Ananya Mandal, MD Common pain and fever Acetaminophen taken over quite a long time can cause liver failure and loss of life, according to a new study. These ‘staggered overdoses’ can occur when folks have ongoing pain and repeatedly have a little more acetaminophen than they should, explained Dr. Kenneth Simpson, of the University of Edinburgh in Scotland, writer of the scholarly study, published Nov.Yet they carry out play a role in regulating cellular curiosity and functions cancer researchers. Researchers at The University of Texas MD Anderson Cancer Center have found that a specific lncRNA called CCAT2 regulates cancer metabolism both in vivo and in vitro. The data was shown on April 20 at the 2015 American Association for Cancers Research Annual Achieving in Philadelphia. ‘Altered energy metabolism is a tumor hallmark as malignant cells tailor their metabolic pathways to meet up their energy requirements,’ said George Calin, M.D., Ph.D., professor of Experimental Therapeutics. ‘In our study, we discovered that CCAT2 regulated cancers metabolism within an allele-specific manner that appears to match a known risk associated with colon cancer.